Prevalence and clinical presentation at the onset of type 1 diabetes mellitus among children and adolescents in AL-Baha region, Saudi Arabia
| Autor: | Ahmed Hassan Al-Ghamdi, Abdelhameed Ahmed Fureeh |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Diabetic ketoacidosis Endocrinology Diabetes and Metabolism Population Saudi Arabia Early detection 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Diabetic Ketoacidosis Young Adult 03 medical and health sciences 0302 clinical medicine Endocrinology Risk Factors Weight loss Diabetes mellitus Prevalence medicine Humans Age of Onset Child education Retrospective Studies Type 1 diabetes education.field_of_study business.industry Body Weight Infant Newborn Infant medicine.disease Ketoacidosis Diabetes Mellitus Type 1 Child Preschool Hyperglycemia Pediatrics Perinatology and Child Health Female medicine.symptom Presentation (obstetrics) business |
| Zdroj: | Journal of Pediatric Endocrinology and Metabolism. 31:269-273 |
| ISSN: | 2191-0251 0334-018X |
| Popis: | Background: The objectives were to describe the frequency of clinical presentation at the onset of type 1 diabetes mellitus (T1DM) and to estimate the prevalence of T1DM among children and adolescents in the AL-Baha region, Saudi Arabia, aiming for early diagnosis of T1DM. Methods: The clinical and laboratory data of 471 children and adolescents who presented with T1DM and received medical care at an AL-Baha diabetic center during the period from 2007 to 2016 were retrospectively analyzed based on the records. Results: The prevalence of T1DM in the AL-Baha region was 355 per 100,000 population in participants aged from 0 to 19 years. T1DM was more common among girls than boys (57.5% vs. 42.5%, respectively; p=0.3), and the female/male ratio was 1.36 in favor of girls. Hyperglycemic symptoms were the most frequent symptoms at presentation [59.2% vs. 40.8% with diabetic ketoacidosis (DKA)], and 37% of them presented with loss of weight. Most of the ketoacidosis was mild to moderate (80.2%), while only 19.8% of children had the severe type and DKA was more common (55.2%) among females. The mean age at diagnosis of T1DM was 8.2±3.5 years for all patients, and 8.3±3.9 and 8.9±3.6 years for boys and girls, respectively (p=0.06). Hyperglycemic symptoms were more common in spring (15.9%). Conclusions: The prevalence of type 1 diabetes in the AL-Baha region was 355 per 100,000 population, which is one of the highest reported prevalences in this age group. Hyperglycemic symptoms were the most encountered symptoms at the onset of the presentation of T1DM and this may help in early detection of diabetic symptoms by patients and physicians to avoid the more severe types of presentation. |
| Databáze: | OpenAIRE |
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