Phytochemical, anti-Acanthamoeba, and anti-adhesion properties of Garcinia mangostana flower as preventive contact lens solution

Autor: Suthinee Sangkanu, Watcharapong Mitsuwan, Tooba Mahboob, Wilawan Mahabusarakam, Sopa Chewchanwuttiwong, Panisara Siphakdi, Tajudeen O. Jimoh, Polrat Wilairatana, Karma G. Dolma, Maria de Lourdes Pereira, Mohammed Rahmatullah, Christophe Wiart, Roghayeh Norouzi, Abolghasem Siyadatpanah, Polydor Ngoy Mutombo, Veeranoot Nissapatorn
Rok vydání: 2022
Předmět:
Zdroj: Acta Tropica. 226:106266
ISSN: 0001-706X
DOI: 10.1016/j.actatropica.2021.106266
Popis: Acanthamoeba keratitis infection extends due to the growing number of contact lens users. Indigenous plants including Garcinia mangostana play a vital role in human health and well being. Many species of this plant have been reported with myriads of potent medicinal properties. However, the aims of this study were, for the first time, to isolate compounds from the flower of G. mangostana and to test their anti-Acanthamoeba and anti-adhesion activity against Acanthamoeba triangularis. Powdered flowers of G. mangostana were extracted and chromatographed on a silica gel column. The structures of the compounds were established with the aid of
Databáze: OpenAIRE