Treatment failure with propranolol for subglottic haemangioma
| Autor: | Zhaobo Liu, Conor Jackson, Yen Huan Yeo, Keith Trimble |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Stridor Adrenergic beta-Antagonists Administration Oral Propranolol Biphasic stridor Treatment failure 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Infantile haemangioma Bronchoscopy medicine Humans Treatment Failure 030223 otorhinolaryngology Laryngeal Neoplasms Respiratory Sounds medicine.diagnostic_test business.industry Infant General Medicine Surgery body regions Safety profile Histopathology medicine.symptom Hemangioma business Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect medicine.drug |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2018-227135 |
| Popis: | The use of propranolol for the treatment of subglottic haemangioma has become hugely popular due to its effectiveness and safety profile. We report a case of 7-month-old boy who presented with stridor and histopathology suggestive of subglottic haemangioma following microlaryngoscopy and bronchoscopy (MLB). However, he did not respond to propranolol treatment. This could be due to an older age of propranolol commencement. In general, early commencement of propranolol is necessary when diagnosis of symptomatic infantile haemangioma is made to achieve maximal improvement in symptoms and prevent further proliferation. There should be a high index of suspicion for subglottic haemangioma in children presenting with chronic biphasic stridor, with early MLB and diagnosis. This will allow early treatment, giving the best chance to avoid our situation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|