Plant anticancer agents. XXVI. Constituents of Peddiea fischeri
| Autor: | Norman R. Farnsworth, Sukhdev S. Handa, A. D. Kinghorn, Geoffrey A. Cordell |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Pharmaceutical Science
Biology Umbelliferone Analytical Chemistry chemistry.chemical_compound Mice Drug Discovery Botany Daphnoretin Animals Peddiea Cells Cultured Pharmacology Chromatography Plants Medicinal Leukemia P388 Organic Chemistry Biological activity biology.organism_classification Antineoplastic Agents Phytogenic Quinone Complementary and alternative medicine chemistry Biochemistry Molecular Medicine Thymelaeaceae P388 leukemia |
| Zdroj: | Journal of natural products. 46(2) |
| ISSN: | 0163-3864 |
| Popis: | The in vitro P-388 lymphocytic leukemia activity of the chloroform-soluble fraction of the roots of Peddiea fischeri (Thymelaceaceae) was found to be due principally to the quinone 2,6-dimethoxybenzoquinone (2,6-DMBQ), and to a lesser extent the two coumarins daphnoretin and umbelliferone. This is the first report of the occurrence of 2,6-DMBQ in the family Thymelaeaceae. The occurrence of 2,6-DMBQ in higher plants is reviewed. |
| Databáze: | OpenAIRE |
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