Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori

Autor:	Susumu Izumi, Dai Tsukioka, Takeshi Adachi
Rok vydání:	2017
Předmět:	0106 biological sciences 0301 basic medicine Gene isoform 01 natural sciences Applied Microbiology and Biotechnology Biochemistry Gene Expression Regulation Enzymologic Analytical Chemistry 03 medical and health sciences Dopamine Bombyx mori medicine Animals Protein Isoforms RNA Messenger Cloning Molecular Molecular Biology Cloning Aromatic L-amino acid decarboxylase integumentary system biology fungi Organic Chemistry Brain General Medicine Bombyx biology.organism_classification Molecular biology Ganglia Invertebrate Cell biology Alternative Splicing 010602 entomology 030104 developmental biology Organ Specificity RNA splicing Dopa Decarboxylase Insect Proteins Serotonin Drosophila melanogaster 5' Untranslated Regions Biotechnology medicine.drug
Zdroj:	Bioscience, Biotechnology, and Biochemistry. 81:555-557
ISSN:	1347-6947 0916-8451
Popis:	Dopa decarboxylase (DDC) protein is involved in the synthesis of dopamine and serotonin. Here, we show that in the silkworm Bombyx mori, a novel DDC splicing variant is selectively expressed in the brain and subesophageal ganglia. In Drosophila melanogaster, a neuron-specific isoform of DDC is known to be alternatively spliced in a similar manner.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3953cbc9102a5d03156102a526f3742 https://doi.org/10.1080/09168451.2016.1258987 Zobrazit plný text záznamu