Complete nucleotide sequence of an endogenous retrovirus from the amphibian, Xenopus laevis
| Autor: | Michael Tristem, Roziah Kambol, Peter Kabat |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Duplication
viruses Molecular Sequence Data Xenopus Endogenous retrovirus Sequence alignment Genome Viral Genome Open Reading Frames Viral Proteins Xenopus laevis African clawed toad Retrovirus Proviruses Virology Animals Amino Acid Sequence ORFS Peptide sequence Phylogeny Genetics Base Sequence Genus biology Endogenous Endogenous Retroviruses Nucleic acid sequence Amphibian biology.organism_classification Sequence Alignment |
| Zdroj: | Virology. 311:1-6 |
| ISSN: | 0042-6822 |
| DOI: | 10.1016/s0042-6822(03)00263-0 |
| Popis: | We report the first full-length sequence of an endogenous amphibian retrovirus derived from the African clawed toad Xenopus laevis. The virus, termed Xen1, has one of the largest endogenous retroviral genomes described to date of over 10 kb in length and it also has a relatively complex genomic organisation consisting of LTR-orf1, orf2, gag, pol, env-LTR. Orfs 1 and 2 are novel, duplicated genes of unknown function. Phylogenetic analysis indicates that Xen1 is most closely related to the ε-retroviruses WDSV and WEHV types 1 and 2, which are large, complex exogenous retroviruses present within Walleye fish. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect