Changes in Speckle Tracking Echocardiography Measures of Ventricular Function after Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonary Position
| Autor: | Jason R. Buckley, Qi-Ling Cao, Saibal Kar, Ziyad M. Hijazi, Lazar Mandinov, Raj Makkar, Girish S Shirali, Nicholas Pietris, John F. Rhodes, Michael P. Mullen, Shahryar M. Chowdhury |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Internationality Heart disease Speckle tracking echocardiography Sensitivity and Specificity Article Ventricular Dysfunction Left medicine.artery Internal medicine Pulmonary Valve Replacement medicine Humans Radiology Nuclear Medicine and imaging Heart valve Cardiac imaging Heart Valve Prosthesis Implantation business.industry Reproducibility of Results Equipment Design medicine.disease Pulmonary Valve Insufficiency Equipment Failure Analysis Treatment Outcome medicine.anatomical_structure Echocardiography Heart Valve Prosthesis Pulmonary valve Pulmonary artery Cardiology Elasticity Imaging Techniques Female Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Echocardiography. 32:461-469 |
| ISSN: | 0742-2822 |
| DOI: | 10.1111/echo.12700 |
| Popis: | Patients with free pulmonary regurgitation or mixed pulmonary stenosis and regurgitation and severely dilated right ventricles (RV) show little improvement in ventricular function after pulmonary valve replacement when assessed by traditional echocardiographic markers. We evaluated changes in right and left ventricular (LV) function using speckle tracking echocardiography in patients after SAPIEN transcatheter pulmonary valve (TPV) placement.Echocardiograms were evaluated at baseline, discharge, 1 and 6 months after TPV placement in 24 patients from 4 centers. Speckle tracking measures of function included peak longitudinal strain, strain rate, and early diastolic strain rate. RV fractional area change, tricuspid annular plane systolic excursion, and left ventricular LV ejection fraction were assessed. Routine Doppler and tissue Doppler velocities were measured.At baseline, all patients demonstrated moderate to severe pulmonary regurgitation; this improved following TPV placement. No significant changes were detected in conventional measures of RV or LV function at 6 months. RV longitudinal strain (-16.9% vs. -19.6%, P0.01), strain rate (-0.87 s(-1) vs. -1.16 s(-1) , P = 0.01), and LV longitudinal strain (-16.2% vs. -18.2%, P = 0.01) improved between baseline and 6 month follow-up. RV early diastolic strain rate, LV longitudinal strain rate and early diastolic strain rate showed no change.Improvements in RV longitudinal strain, strain rate, and LV longitudinal strain are seen at 6 months post-TPV. Diastolic function does not appear to change at 6 months. Speckle tracking echocardiography may be more sensitive than traditional measures in detecting changes in systolic function after TPV implantation. |
| Databáze: | OpenAIRE |
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