Sickle cell disease in pregnancy

Autor: Tasneem Singhal, Shazia Nazir, Jo Howard, Eugene Oteng-Ntim
Rok vydání: 2006
Předmět:
Zdroj: Current Obstetrics & Gynaecology. 16:353-360
ISSN: 0957-5847
DOI: 10.1016/j.curobgyn.2006.09.006
Popis: Summary With advances in management, many women with sickle cell disease now survive to have children. The high risk of fetal and maternal sequelae mandates multidisciplinary management involving an obstetrician, a haematologist, an anaesthetist and a haemoglobinopathy specialist nurse. Hydroxyurea, a new treatment for sickle cell disease, is contraindicated in pregnancy. Exchange transfusion may be indicated in women with a serious obstetric or haematological complications. In those with sickle cell disease, the entire pregnancy is a high-risk period that warrants close monitoring. It is thus important for every obstetrician to be familiar with the condition.
Databáze: OpenAIRE