Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review
| Autor: | Mat Hussin Ab Talib, Suhaimi Illias, Sudin Izman, Nor Zaiazmin Yahaya, M. N. B. Omar, A. I. M. Shaiful, Nur Syahirah Mustafa, Nor Hasrul Akhmal |
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| Rok vydání: | 2021 |
| Předmět: |
Scaffold
Polymers and Plastics numerical analysis Computer science 0206 medical engineering ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION Organic chemistry 02 engineering and technology Review simulation software computer.software_genre Bone tissue Bone tissue engineering Software QD241-441 Mechanical strength computational method medicine Triply periodic minimal surface ComputingMethodologies_COMPUTERGRAPHICS business.industry ComputingMilieux_PERSONALCOMPUTING General Chemistry mechanical strength 021001 nanoscience & nanotechnology 020601 biomedical engineering Simulation software medicine.anatomical_structure Biochemical engineering 0210 nano-technology business computer tissue engineering scaffold design |
| Zdroj: | Polymers Polymers, Vol 13, Iss 1584, p 1584 (2021) |
| ISSN: | 2073-4360 |
| Popis: | The design of a scaffold of bone tissue engineering plays an important role in ensuring cell viability and cell growth. Therefore, it is a necessity to produce an ideal scaffold by predicting and simulating the properties of the scaffold. Hence, the computational method should be adopted since it has a huge potential to be used in the implementation of the scaffold of bone tissue engineering. To explore the field of computational method in the area of bone tissue engineering, this paper provides an overview of the usage of a computational method in designing a unit cell of bone tissue engineering scaffold. In order to design a unit cell of the scaffold, we discussed two categories of unit cells that can be used to design a feasible scaffold, which are non-parametric and parametric designs. These designs were later described and being categorised into multiple types according to their characteristics, such as circular structures and Triply Periodic Minimal Surface (TPMS) structures. The advantages and disadvantages of these designs were discussed. Moreover, this paper also represents some software that was used in simulating and designing the bone tissue scaffold. The challenges and future work recommendations had also been included in this paper. |
| Databáze: | OpenAIRE |
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