Prognosis of Fibrosarcoma in Patients With and Without a History of Radiation for Nasopharyngeal Carcinoma
| Autor: | Bo Qiu, Su Ping Guo, Meng Zhong Liu, Qing Liu, Yu Jia Zhu, Yong Li, Lei Zhao, Peng Zhang, Mian Xi |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0301 basic medicine Oncology medicine.medical_specialty Neoplasms Radiation-Induced Adolescent Fibrosarcoma medicine.medical_treatment Metastasis Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Surgical oncology Internal medicine medicine Humans Young adult Stage (cooking) Child Survival rate Aged Nasopharyngeal Carcinoma business.industry Carcinoma Nasopharyngeal Neoplasms Radiotherapy Dosage Middle Aged Prognosis medicine.disease Survival Rate Radiation therapy stomatognathic diseases 030104 developmental biology Nasopharyngeal carcinoma Child Preschool 030220 oncology & carcinogenesis Female Radiotherapy Adjuvant Surgery business Follow-Up Studies |
| Zdroj: | Annals of Surgical Oncology. 24:434-440 |
| ISSN: | 1534-4681 1068-9265 |
| Popis: | To determine whether radiation-induced fibrosarcoma (RIF) in patients with a history of radiotherapy for nasopharyngeal carcinoma (NPC) was associated with an inferior prognosis compared to sporadic fibrosarcoma of the head and neck. Forty-two patients with RIF who previously received radiotherapy for NPC and 124 patients with sporadic fibrosarcoma of the head and neck were identified between January 1965 and December 2013 at our institution. Information on clinicopathologic characteristics and treatment was abstracted from medical records. The primary end point was disease-specific survival (DSS). The median latency from NPC diagnosis to RIF diagnosis was 9.9 years (range 3.1–36.8 years). RIF was diagnosed at an older age than sporadic fibrosarcoma. Treatment modality was significantly different between the two groups, with only 64.3 % of the RIF group receiving surgery ± adjuvant treatment versus 91.1 % in the sporadic fibrosarcoma group (P |
| Databáze: | OpenAIRE |
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