Association between genital mycoplasma and cervical squamous cell atypia
| Autor: | Ahmed Walid Anwar Morad, Aymen Azzazi, Mohamed A. Elhadi Farag, Sahar M. Fayed, Ahmed Kasem Zain Eldin |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pathology lcsh:QH471-489 HSIL LSIL Mycoplasma hominis Cervical atypia medicine.disease_cause Obstetrics and gynaecology Obstetrics and Gynaecology medicine Atypia lcsh:Reproduction Gynecology lcsh:R5-920 Clinical pathology biology business.industry Obstetrics and Gynecology Cervical Atypia Mycoplasma biology.organism_classification medicine.disease ASCUS female genital diseases and pregnancy complications Reproductive Medicine lcsh:Medicine (General) business Ureaplasma urealyticum Ascus |
| Zdroj: | Middle East Fertility Society Journal, Vol 18, Iss 4, Pp 241-245 (2013) |
| ISSN: | 1110-5690 |
| DOI: | 10.1016/j.mefs.2013.01.003 |
| Popis: | Objectives To investigate the existence of an association between genital mycoplasma infections and cervical squamous cell atypia. Study design Prospective cross-sectional study. Setting Department of Obstetrics and Gynecology, in collaboration with the Clinical Pathology and Pathology Departments, Faculty of Medicine, Benha University, Egypt. Patients and methods Three-hundred women were scheduled into two equal groups. The control group included 150 women with negative Pap smear for cervical atypia. The study group included 150 women with cervical squamous cell atypia proved by Pap smear. Swabs obtained from endocervix and posterior vaginal fornix were subjected to culture for detection of genital mycoplasma using Mycoplasma IST2. Outcome measures were the rates of cervicovaginal infection with genital mycoplasma in both groups, and estimation of the co-occurrence of genital mycoplasma and cervical squamous cell atypia. Results Using Mycoplasma IST2 kit genital mycoplasmas were positive in (49.33% vs. 28.67%) of cases in study and control groups, respectively. Ureaplasma urealyticum was isolated more frequent than mycoplasma hominis and mixed mycoplasma infection. U. urealyticum colonization was demonstrated in women with HSIL (57.5%) significantly more frequent compared to women with LSIL (36.59%), ASCUS (30.43%), and with normal cytology (21.33%); P = 0.019. Conclusion Ureaplasma urealyticum was present significantly more often in women with cervical cytological atypia, suggesting the existence of an association between cervicovaginal infections with U. urealyticum and precancerous lesions of the uterine cervix. |
| Databáze: | OpenAIRE |
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