Phytochemistry and antimicrobial activity of Campomanesia adamantium
| Autor: | Luiza Toubas Chaul, Boniek G. Vaz, Leonardo Luiz Borges, Virgínia Farias Alves, Leonice M.F. Tresvenzol, José Realino de Paula, Tatiana de Sousa Fiuza, Stone de Sá, Pedro Henrique Ferri |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Phytochemistry
Gallic acid Stictane-3 22-diol Ethyl acetate Valoneic acid Sabinene lcsh:RS1-441 Campomanesia 01 natural sciences lcsh:Pharmacy and materia medica chemistry.chemical_compound Tannin General Pharmacology Toxicology and Pharmaceutics chemistry.chemical_classification Limonene Chromatography biology Phytochemical study 010401 analytical chemistry Cerrado biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry Phytochemical chemistry Broth microdilution |
| Zdroj: | Revista Brasileira de Farmacognosia v.28 n.3 2018 Revista Brasileira de Farmacognosia Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA Revista Brasileira de Farmacognosia, Vol 28, Iss 3, Pp 303-311 Revista Brasileira de Farmacognosia, Vol 28, Iss 3, Pp 303-311 (2018) Revista Brasileira de Farmacognosia, Volume: 28, Issue: 3, Pages: 303-311, Published: JUN 2018 |
| Popis: | Campomanesia adamantium (Cambess.) O. Berg., Myrtaceae, is a plant popularly used for its anti-inflammatory, anti-diarrhoeal and urinary antiseptic activities. The aims of this study were to obtain the crude ethanolic extract and the hexane, dichloromethane, ethyl acetate, aqueous and concentrated aqueous tannin fractions from C. adamantium leaves, perform biomonitored fractionation to isolate and identify chemical compounds, study the chemical composition of the volatile oils of the leaves and flowers and test the antimicrobial activity of the ethanolic extract, fractions, isolated substances and volatile oils. Phytochemical screening and chromatographic and spectrometric techniques were used. Volatile oils were isolated by hydrodistillation in a Clevenger apparatus and analyzed by gas chromatography/mass spectrometry. The antimicrobial activity was tested by a broth microdilution test. The component stictane-3,22-diol was isolated and identified from the hexane fraction, while valoneic and gallic acid were isolated and identified from the concentrated aqueous tannin fraction. The major constituents of the volatile oils of the leaves were verbenene (13.91%), β-funebrene (12.05%) and limonene (10.32%), while those of the volatile oils of the flowers were sabinene (20.45%), limonene (19.33%), α-thujene (8.86%) and methyl salicylate (8.66%). Antibacterial activity was verified for the hexane fraction, while antifungal activity was observed for the aqueous fraction and concentrated aqueous tannin fraction and for vanoleic acid. These results may justify the popular use of C. adamantium. Keywords: Valoneic acid, Stictane-3,22-diol, Gallic acid, Phytochemical study, Broth microdilution, Cerrado |
| Databáze: | OpenAIRE |
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