Quantitative evaluation of Streptococcus mutans and Candida sp and salivary factors in the oral cavity of patients submitted to radiotherapy

Autor: J F Höfling, R H Barbeiro, W L Bernardo, S Pavan, L C Spolidorio, Denise Madalena Palomari Spolidorio
Přispěvatelé: Universidade Estadual Paulista (Unesp), Universidade Estadual de Campinas (UNICAMP)
Jazyk: portugalština
Rok vydání: 2001
Předmět:
Zdroj: Pesquisa Odontológica Brasileira, Volume: 15, Issue: 4, Pages: 354-358, Published: DEC 2001
Pesquisa Odontológica Brasileira; Vol. 15 No. 4 (2001); 354-358
Pesquisa Odontológica Brasileira; Vol. 15 Núm. 4 (2001); 354-358
Pesquisa Odontológica Brasileira; v. 15 n. 4 (2001); 354-358
Pesquisa odontológica brasileira
Universidade de São Paulo (USP)
instacron:USP
Pesquisa Odontológica Brasileira, Vol 15, Iss 4, Pp 354-358 (2001)
SciELO
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Pesquisa Odontológica Brasileira, Vol 15, Iss 4, Pp 354-358
ISSN: 1517-7491
1678-8079
Popis: Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:41:13Z No. of bitstreams: 1 S1517-74912001000400014.pdf: 117836 bytes, checksum: ba181a813e12f538acf20bb47e663899 (MD5) Made available in DSpace on 2013-08-22T18:41:13Z (GMT). No. of bitstreams: 1 S1517-74912001000400014.pdf: 117836 bytes, checksum: ba181a813e12f538acf20bb47e663899 (MD5) Previous issue date: 2001-12-01 Made available in DSpace on 2013-09-30T19:27:37Z (GMT). No. of bitstreams: 2 S1517-74912001000400014.pdf: 117836 bytes, checksum: ba181a813e12f538acf20bb47e663899 (MD5) S1517-74912001000400014.pdf.txt: 21489 bytes, checksum: e70f6aceca34fb169390d2134a03f0fd (MD5) Previous issue date: 2001-12-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:45:51Z No. of bitstreams: 2 S1517-74912001000400014.pdf: 117836 bytes, checksum: ba181a813e12f538acf20bb47e663899 (MD5) S1517-74912001000400014.pdf.txt: 21489 bytes, checksum: e70f6aceca34fb169390d2134a03f0fd (MD5) Made available in DSpace on 2014-05-20T13:45:51Z (GMT). No. of bitstreams: 2 S1517-74912001000400014.pdf: 117836 bytes, checksum: ba181a813e12f538acf20bb47e663899 (MD5) S1517-74912001000400014.pdf.txt: 21489 bytes, checksum: e70f6aceca34fb169390d2134a03f0fd (MD5) Previous issue date: 2001-12-01 O objetivo deste trabalho foi analisar quantitativamente os microrganismos, Streptococcus do grupo mutans e Candida sp, da cavidade bucal de pacientes com carcinoma de orofaringe antes, durante e após o tratamento com radioterapia e correlacionar fatores salivares como pH, capacidade tampão (CT) e fluxo salivar (FS). Amostras de saliva foram coletadas, diluídas e inoculadas em ágar SB-20 e ágar Sabouraud, respectivamente para Streptococcus do grupo mutans e Candida sp. Previamente à diluição, a saliva concentrada foi analisada, determinando-se os fatores salivares. Após crescimento das colônias, o número de microrganismos foi determinado em UFC/ml. A análise dos resultados permitiu concluir que houve correlação positiva entre os fatores salivares e a presença de microrganismos ilustrada pelo aumento no número de UFC/ml dos microrganismos analisados concomitantemente com a diminuição do fluxo salivar. Os efeitos da radiação comprometeram a homeostasia salivar e favoreceram o aumento das infecções por leveduras e bactérias durante o tratamento radioterápico. The aim of this study was to quantify the microorganisms Streptococcus mutans and Candida sp in the oral cavity of patients with oropharynx carcinoma, before, during and after radiotherapy, and to correlate the results with salivary factors such as pH, buffer capacity (CT) and flow rate (FS). Saliva samples were collected, diluted and inoculated in SB-20 agar and in Sabouraud agar, for Streptococcus mutans and Candida sp, respectively. Previously to dilution, the concentrated saliva was analyzed, and the salivary factors were determined. After the growth of colonies, the number of microorganisms was determined in CFU/ml. The analysis of the results allowed to conclude that the salivary factors are related to the presence of microorganisms, and that the number of CFU/ml increased as salivary flow rate decreased. The effects of radiation compromised salivary homeostasis and favored the increase of infection by yeasts and bacteria. Universidade Estadual Paulista Faculdade de Odontologia de Araraquara Universidade de Campinas Faculdade de Odontologia de Piracicaba Universidade Estadual Paulista Faculdade de Odontologia de Araraquara
Databáze: OpenAIRE