Low serum cortisol predicts early death after acute myocardial infarction
| Autor: | F G Dunn, Rebecca M. Reynolds, Paul D MacIntyre, Alastair C H Pell, David Murdoch, Keith G. Oldroyd, Brian O’Rourke, Daniel F. Mackay, David E. Newby, Jill P. Pell, Brian R. Walker, Stuart D. Pringle, Sally Haw, Stuart M. Cobbe, Colin Fischbacher |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Hydrocortisone Myocardial Infarction acute myocardial infarction Critical Care and Intensive Care Medicine Cohort Studies nested case-control study Internal medicine Intensive care Adrenal insufficiency Humans Medicine Hospital Mortality Prospective Studies Myocardial infarction Prospective cohort study Aged Aged 80 and over business.industry Case-control study Middle Aged Prognosis medicine.disease mortality Survival Analysis Troponin Intensive Care Units Endocrinology Scotland Case-Control Studies Nested case-control study Cardiology Female adrenal insufficiency business hormones hormone substitutes and hormone antagonists Glucocorticoid Follow-Up Studies medicine.drug |
| Zdroj: | Critical Care Medicine. 38:973-975 |
| ISSN: | 0090-3493 |
| DOI: | 10.1097/ccm.0b013e3181cdf6de |
| Popis: | Objective: To determine whether low serum cortisol concentrations are associated with adverse prognosis in patients with acute myocardial infarction. Low serum cortisol concentrations have been associated with adverse prognosis in critical illness of diverse etiology. Design: Nested case-control study. Setting: Prospective cohort study of consecutive patients admitted with acute myocardial infarction to nine Scottish hospitals. Patients: A total of 100 patients who survived 30 days (controls) and 100 patients who died within 30 days (cases). Measurements and Main Results: Admission cortisol concentrations were lower in patients who died than those who survived (median, 1189 nmol/L vs. 1355 nmol/L; p < .001). A cortisol concentration in the bottom quartile ( |
| Databáze: | OpenAIRE |
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