Comparison of organophosphorous acid anhydrolases from different species using monoclonal antibodies
| Autor: | Karla Kopec-Smyth, Jennifer L. Poppino, Susan L. Futrovsky, Jeffrey R. Deschamps, Keith B. Ward |
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| Rok vydání: | 1993 |
| Předmět: |
Substrate Specificities
Anticorps monoclonal medicine.drug_class Immunology Enzyme-Linked Immunosorbent Assay Viper Venoms Monoclonal antibody Epitope Substrate Specificity Epitopes Mice medicine Animals Optic ganglion Pharmacology chemistry.chemical_classification Mice Inbred BALB C biology Aryldialkylphosphatase Decapodiformes Esterases Antibodies Monoclonal biology.organism_classification Molecular biology Enzyme chemistry Biochemistry Female Hepatopancreas |
| Zdroj: | Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 106:765-768 |
| ISSN: | 0742-8413 |
| Popis: | 1. Monoclonal antibodies were raised against squid hepatopancreas organophosphorous acid (OPA) anhydrolase (EC 3.1.8.2) and were used to study structural similarities with OPA anhydrolases isolated from different sources. 2. Common epitopes were identified in OPA anhydrolases with diverse origins, and with different substrate specificities. 3. Epitopes unique to the squid hepatopancreas OPA anhydrolase were identified; optic ganglion and hepatopancreas contain different enzymes which can be distinguished by their epitopes. |
| Databáze: | OpenAIRE |
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