The influence of lipoproteins on whole-blood viscosity at multiple shear rates

Autor: Arnold H. Slyper, Anh Le, Jason W. Jurva, David D. Gutterman
Rok vydání: 2005
Předmět:
Zdroj: Metabolism: clinical and experimental. 54(6)
ISSN: 0026-0495
Popis: Whole-blood viscosity appears to be an independent predictor of stroke, carotid intima-media thickening, and carotid atherosclerosis. The purpose of this study was to examine for relationships between whole-blood viscosity and blood lipids in young healthy subjects over a range of shear rates. Twenty-seven healthy men and women aged 10 to 25 years having a range of low-density lipoprotein (LDL) cholesterol values 88 to 258 mg/dL and body mass index z scores -1.18 to 2.64 SDs were studied. Whole-blood viscosity at shear rates from 1 to 1000 per second was measured using an automated capillary viscometer. Blood lipids were measured using standard techniques. Triglyceride-rich lipoproteins were isolated by ultracentrifugation at density of
Databáze: OpenAIRE