The influence of lipoproteins on whole-blood viscosity at multiple shear rates
Autor: | Arnold H. Slyper, Anh Le, Jason W. Jurva, David D. Gutterman |
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Rok vydání: | 2005 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Blood lipids Lipoprotein particle Viscosity chemistry.chemical_compound Endocrinology Internal medicine medicine Humans Particle Size Child biology Apolipoprotein A-I Chemistry Cholesterol Cholesterol HDL Viscometer Lipoprotein(a) Cholesterol LDL Blood Viscosity Lipids Shear rate biology.protein Regression Analysis lipids (amino acids peptides and proteins) Female Shear Strength Lipoprotein |
Zdroj: | Metabolism: clinical and experimental. 54(6) |
ISSN: | 0026-0495 |
Popis: | Whole-blood viscosity appears to be an independent predictor of stroke, carotid intima-media thickening, and carotid atherosclerosis. The purpose of this study was to examine for relationships between whole-blood viscosity and blood lipids in young healthy subjects over a range of shear rates. Twenty-seven healthy men and women aged 10 to 25 years having a range of low-density lipoprotein (LDL) cholesterol values 88 to 258 mg/dL and body mass index z scores -1.18 to 2.64 SDs were studied. Whole-blood viscosity at shear rates from 1 to 1000 per second was measured using an automated capillary viscometer. Blood lipids were measured using standard techniques. Triglyceride-rich lipoproteins were isolated by ultracentrifugation at density of |
Databáze: | OpenAIRE |
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