An inulin-type fructan (AMP1-1) from Atractylodes macrocephala with anti-weightlessness bone loss activity

Autor:	Rui Wang, Hailing Shan, Guanjun Zhang, Qiao Li, Jinpeng Wang, Qiuxin Yan, Erzhuo Li, Yan Diao, Lijun Wei
Rok vydání:	2022
Předmět:	Molecular Weight Polymers and Plastics Polysaccharides Organic Chemistry Materials Chemistry Inulin Atractylodes Fructans
Zdroj:	Carbohydrate polymers. 294
ISSN:	1879-1344
Popis:	Atractylodes macrocephalon polysaccharides of alleviating weightlessness-induced bone loss (WIBL) are rarely reported. In this study, a neutral polysaccharide fragment named AMP1-1 was isolated and purified. Monosaccharide composition and gel permeation chromatography analysis indicated that AMP1-1 was composed of glucose and fructose with molecular weight of 1.433 kDa. Based on data of gas chromatography-mass spectrometer (GCMS), a linear backbone consisted of α-d-Glcp-(1→ and →1)-β-d-Fruf-2→ was discovered. Combining results from nuclear magnetic resonance (NMR), the inulin-type fructan AMP1-1 was identified as α-d-Glcp-1→(2-β-d-Fruf-1)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d349ed083d83482594d839781a0554af https://pubmed.ncbi.nlm.nih.gov/35868743 Zobrazit plný text záznamu Full Text from ScienceDirect