Extragastrointestinal stromal tumor presenting as a scrotal mass: First report from India
| Autor: | Vishal Bansal, Qutubuddin Ali, Krishnanand Anand |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty EGIST Article CD117 Abdominal wall 03 medical and health sciences 0302 clinical medicine Scrotum medicine Stromal tumor Gastrointestinal tract biology GiST business.industry Left Testis digestive system diseases medicine.anatomical_structure 030220 oncology & carcinogenesis biology.protein Abdomen 030211 gastroenterology & hepatology Surgery CD34 Gastrointestinal stromal tumor business |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| DOI: | 10.1016/j.ijscr.2020.05.079 |
| Popis: | Highlights • Gastrointestinal Stromal tumours (GIST) are the most common mesenchymal tumors that arises from the wall of the gastrointestinal tract. • Similar tumours elsewhere in the abdomen are called extra gastrointestinal stromal tumor (EGIST). • We describe an unusual case of EGIST presenting as a primary scrotal mass. • Left inguinal orchidectomy along with excision of mass was done. • HPE revealed a spindle cell pattern with low cellularity and IHC analysis revealed the tumor reactive for CD117 and CD34 which is suggestive of GIST. Introduction Gastrointestinal Stromal Tumours (GIST) are the most common mesenchymal tumours that arises from the wall of the gastrointestinal tract. Similar tumours elsewhere in the abdomen are called extra gastrointestinal stromal tumor (EGIST). Presentation of case A 68 years male presented with a gradually enlarging scrotal mass over a period of 6month duration. On examination a mass was felt (5 cm × 4 cm) occupying left side of scrotum and abutting the lower pole of left testis. Left inguinal orchidectomy along with excision of mass was done. HPE revealed a spindle cell pattern with low cellularity and Immunohistochemical analysis revealed the tumor reactive for CD 117 and CD 34 which is suggestive of GIST. Discussion EGIST have been reported in unusual locations, including the pancreas, prostate, and abdominal wall. The occurrence of EGIST is extremely rare and little is known about their actual origin. The diagnosis is by the demonstration of a specific marker CD 117 and CD34. We describe an unusual case of extra gastrointestinal stromal tumor (EGIST) presenting as a primary scrotal mass. Conclusion To the best of our knowledge, this is the first Indian case of an EGIST involving the scrotum as primary site and second such case worldwide. |
| Databáze: | OpenAIRE |
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