Perception of Breathlessness by a 3-Minute Respiratory Exerciser Test Predicts Asthma Exacerbations: A Prospective Cohort Study
Autor: | Li-Cher Loh, Pek-Ngor Teh |
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Rok vydání: | 2009 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Pediatrics medicine.medical_specialty Office Visits Sensitivity and Specificity Severity of Illness Index Cohort Studies Young Adult Patient Admission Risk Factors Humans Immunology and Allergy Medicine Prospective Studies Respiratory system Prospective cohort study Asthma Asthma exacerbations business.industry Equipment Design Middle Aged medicine.disease Test (assessment) Dyspnea Breath Tests ROC Curve Pediatrics Perinatology and Child Health Hospital admission Female Perception business |
Zdroj: | Journal of Asthma. 46:529-534 |
ISSN: | 1532-4303 0277-0903 |
Popis: | We prospectively evaluated the use of a simple 3-Minute Respiratory Exerciser Test (3MRET) that estimates perception of dyspnea to identify patients at risk of asthma exacerbations. A total of 146 stable asthmatics (42 under-perceivers, 69 normal perceivers, and 35 over-perceivers) received follow-up for 12 months. The mean (SD) unscheduled visits to doctors among under-, normal, and over-perceivers were 1.8 (1.2), 2.2 (1.8), and 3.1 (2.3), respectively (p = 0.008). The mean (SD) hospital admissions among the groups were 1.3 (0.5), 1.2 (0.6), and 1.7 (1.3), respectively (p = 0.026). Compared to normal perceivers, over-perceivers had increased risks of unscheduled visits (OD: 5.12; 95% CI = 1.59 to 16.47) and hospital admissions (OD: 0.31; 95% CI = 0.23 to 0.41), defined asor =2 events in 12 months. The association between over-perceiver and unscheduled visits remained significant after adjusting for forced expiratory volume in 1 second (FEV(1)). Sensitivity and specificity of over-perceivers are 77% and 47%, respectively, for unscheduled visits and 37% and 78%, respectively, for hospital admissions, with significantly better area under ROC for unscheduled visits (0.67 [95% CI = 0.56 to 0.77]; p = 0.003) than for hospital admissions (0.58 [0.471 to 0.70]; p = 0.127). We conclude that the 3MRET may have a role in identifying asthmatic patients with over-perception of dyspnea at risk of clinically important asthma exacerbations. |
Databáze: | OpenAIRE |
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