Glycosylated-Chitosan Derivatives: A Systematic Review
| Autor: | Michela Cok, Ivan Donati, Chiara Pizzolitto, Pasquale Sacco, Andrea Marfoglia, Francesca Scognamiglio, Federica Vecchies, Eleonora Marsich |
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| Přispěvatelé: | Sacco, Pasquale, Cok, Michela, Scognamiglio, Francesca, Pizzolitto, Chiara, Vecchies, Federica, Marfoglia, Andrea, Marsich, Eleonora, Donati, Ivan |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Glycosylation
Pharmaceutical Science Oligosaccharides Nanotechnology Biocompatible Materials macromolecular substances Review engineering.material Molecular Dynamics Simulation glycosylated-chitosan derivative drug/gene delivery applications Analytical Chemistry Chitosan lcsh:QD241-441 chemistry.chemical_compound Drug Delivery Systems lcsh:Organic chemistry Drug Discovery Animals Humans Physical and Theoretical Chemistry drug/gene delivery application tissue engineering applications chemical synthesi Tissue Engineering Organic Chemistry physical-chemical propertie glycosylated-chitosan derivatives physical-chemical properties carbohydrates (lipids) chemistry Chemistry (miscellaneous) Drug delivery engineering Molecular Medicine Nanoparticles chemical synthesis chitosan Biopolymer |
| Zdroj: | Molecules Molecules, Vol 25, Iss 1534, p 1534 (2020) |
| ISSN: | 1420-3049 |
| Popis: | Chitosan derivatives, and more specifically, glycosylated derivatives, are nowadays attracting much attention within the scientific community due to the fact that this set of engineered polysaccharides finds application in different sectors, spanning from food to the biomedical field. Overcoming chitosan (physical) limitations or grafting biological relevant molecules, to mention a few, represent two cardinal strategies to modify parent biopolymer; thereby, synthetizing high added value polysaccharides. The present review is focused on the introduction of oligosaccharide side chains on the backbone of chitosan. The synthetic aspects and the effect on physical-chemical properties of such modifications are discussed. Finally, examples of potential applications in biomaterials design and drug delivery of these novel modified chitosans are disclosed. |
| Databáze: | OpenAIRE |
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