Gallbladder Cancer in the Netherlands: Incidence, Treatment and Survival Patterns since 1989
| Autor: | Sanne A.W. van den Akker, Otto Visser, Caroline D.M. Witjes, Cornelis Verhoef, Jan N. M. IJzermans, Robert A. de Man, Henrike E. Karim-Kos, Esther de Vries, Jan Willem Coebergh |
|---|---|
| Přispěvatelé: | Surgery, Public Health, Internal Medicine, Gastroenterology & Hepatology |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Cancer registration Risk Assessment Disease-Free Survival Age Distribution SDG 3 - Good Health and Well-being Epidemiology of cancer medicine Humans Western world Cholecystectomy Neoplasm Invasiveness Registries Sex Distribution Gallbladder cancer education Aged Neoplasm Staging Netherlands Retrospective Studies Aged 80 and over education.field_of_study business.industry Incidence General surgery Incidence (epidemiology) Gastroenterology Middle Aged Prognosis medicine.disease Survival Analysis Treatment Outcome Chemotherapy Adjuvant Female Gallbladder Neoplasms Radiotherapy Adjuvant Surgery business |
| Zdroj: | Digestive Surgery, 29(2), 92-98. Karger |
| ISSN: | 1421-9883 0253-4886 |
| DOI: | 10.1159/000336217 |
| Popis: | Background: To examine recent trends in gallbladder cancer (GBC) in the general population in the Western world, cancer registration data on GBC in the Netherlands were analyzed. Methods: Trends in incidence, treatment and survival, according to gender, age and stage of disease, between 1989 and 2008 for 3,917 patients were studied. Rates were age-standardized to the European standard population (European Standardized Rates – ESR). Results: The incidence rate for GBC in the Netherlands decreased rapidly during the period of 1989–2008, except for males younger than 60 years. Overall survival remained stable, short-term (3-month) and long-term (5-year) relative survival among surgically treated patients increased significantly. Treatment patterns for GBC changed. Surgery decreased from 55% in 1989 to 38% in 2008 (p < 0.001). Chemotherapy and/or irradiation increased from 1.0 to 5.8% (p < 0.001). Receiving best supportive care increased from 44% in 1989 to 57% in 2008 (p < 0.001). Conclusion: The incidence rate for GBC in the Netherlands has decreased rapidly. Treatment patterns for GBC have changed and survival among surgically treated patients has increased. |
| Databáze: | OpenAIRE |
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