Head and neck carcinoma in Fanconi's anaemia—report of a case and review of the literature

Autor: E. Sigler, J.P. Lustig, G. Lugassy, A. Neder
Rok vydání: 1995
Předmět:
Zdroj: European Journal of Cancer Part B: Oral Oncology. 31:68-72
ISSN: 0964-1955
Popis: Fanconi's anaemia (FA) is a rare autosomal recessive syndrome characterised by progressive lethal pancytopenia, skeletal abnormalities, hyperpigmentation and increased chromosomal aberrations. A high incidence of leukaemia and hepatocellular and squamous cell carcinomas (SCC) have been reported in FA patients. A rare case of SCC of the dorsum of the tongue in a FA patient is presented. A review of the reported cases of head and neck carcinoma in FA patients shows a different male: female ratio than previously reported, and a high incidence of carcinoma of the tongue.
Databáze: OpenAIRE