Echocardiographic parameters for the assessment of congestive heart failure in dogs with myxomatous mitral valve disease and moderate to severe mitral regurgitation
| Autor: | Sonja Fonfara, K.R.S. Morgan, Gabrielle Monteith, S. Raheb, M. Colpitts |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Moderate to severe Cardiac function curve medicine.medical_specialty 040301 veterinary sciences Heart Valve Diseases Disease 030204 cardiovascular system & hematology 0403 veterinary science 03 medical and health sciences Dogs 0302 clinical medicine Internal medicine medicine Animals Dog Diseases Heart Atria cardiovascular diseases Myxomatous mitral valve Retrospective Studies Heart Failure Mitral regurgitation Mitral Valve Prolapse General Veterinary business.industry Mitral Valve Insufficiency 04 agricultural and veterinary sciences medicine.disease Echocardiography Heart failure cardiovascular system Cardiology Mitral Valve Female Animal Science and Zoology Mitral valve regurgitation business Isovolumic relaxation time |
| Zdroj: | The Veterinary Journal. 263:105518 |
| ISSN: | 1090-0233 |
| DOI: | 10.1016/j.tvjl.2020.105518 |
| Popis: | The objective of this study was to evaluate the influence of congestive heart failure (CHF) on echocardiographic variables in dogs with moderate or severe mitral valve regurgitation (MR) secondary to myxomatous mitral valve disease (MMVD). The secondary objective was to investigate the preliminary use of left ventricular early inflow-outflow index (LVEIO) and L-waves as indicators of CHF. Forty-five dogs with moderate or severe MR without (n = 23) or with (n = 22) CHF were retrospectively included. Echocardiographic variables of elevated left ventricular (LV) filling pressures and cardiac function, LVEIO and the presence of L-waves were obtained and statistically compared between the two groups. On general linear model analysis, mitral inflow peak E-wave velocity, E:A ratio, ratio of E to isovolumic relaxation time (IVRT) and LVEIO were increased, while left atrium (LA) fractional shortening was reduced, in dogs with CHF. Peak E-wave velocity, peak A-wave velocity, E:A ratio, LA minimum diameter, LA diameter before the P-wave, LA fractional shortening and LVEIO were found to be predictive of CHF. The absence of L-waves indicated a reduced risk of CHF. Several echocardiographic variables may be useful in identifying elevated LV filling pressures, consistent with CHF, in dogs with moderate and severe MR. Left ventricular early inflow-outflow index and L-waves might be of interest as clinical and prognostic markers in dogs with MMVD and require further investigation. |
| Databáze: | OpenAIRE |
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