Individual and Binary Mixture Toxicity of Five Nanoparticles in Marine Microalga Heterosigma akashiwo
| Autor: | Seyed Ali Johari, Konstantin Pikula, Kirill Golokhvast, Ralph Santos-oliveira |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
cadmium sulfide
ecotoxicology flow cytometry mesoporous silicon dioxide microalgae bioassay mixture toxicity particle agglomeration titanium dioxide Trojan horse effect zinc sulfide QH301-705.5 Organic Chemistry technology industry and agriculture General Medicine Catalysis Computer Science Applications Inorganic Chemistry Chemistry Physical and Theoretical Chemistry Biology (General) Molecular Biology QD1-999 Spectroscopy |
| Zdroj: | International Journal of Molecular Sciences, Vol 23, Iss 990, p 990 (2022) International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 990 |
| ISSN: | 1661-6596 1422-0067 |
| Popis: | The investigation of the combined toxic action of different types of nanoparticles (NPs) and their interaction between each other and with aquatic organisms is an important problem of modern ecotoxicology. In this study, we assessed the individual and mixture toxicities of cadmium and zinc sulfides (CdS and ZnS), titanium dioxide (TiO2), and two types of mesoporous silicon dioxide (with no inclusions (SMB3) and with metal inclusions (SMB24)) by a microalga growth inhibition bioassay. The counting and size measurement of microalga cells and NPs were performed by flow cytometry. The biochemical endpoints were measured by a UV-VIS microplate spectrophotometer. The highest toxicity was observed for SMB24 (EC50, 3.6 mg/L) and CdS (EC50, 21.3 mg/L). A combined toxicity bioassay demonstrated that TiO2 and the SMB3 NPs had a synergistic toxic effect in combinations with all the tested samples except SMB24, probably caused by a “Trojan horse effect”. Sample SMB24 had antagonistic toxic action with CdS and ZnS, which was probably caused by metal ion scavenging. |
| Databáze: | OpenAIRE |
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