Manganese and the cGAS-STING Pathway in Infectious Mononucleosis Caused by Epstein-Barr Virus Infection

Autor: Jinjin Shi, Yuqin Li, Dandan Zhang, Min Yu, Weifang Zhou
Rok vydání: 2022
Předmět:
Zdroj: Viral immunology.
ISSN: 1557-8976
Popis: To study the clinical significance of manganese (Mn) in the serum of children with infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV) infection, we analyzed the correlation between Mn and the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway and explored the immune pathogenesis of EBV infection. Children diagnosed with IM comprised the IM group, and healthy children during the same period were selected as the normal control group. Real-time reverse transcription-polymerase chain reaction was used to detect the mRNA expression levels of
Databáze: OpenAIRE