Ectopic recurrence of dysplastic gangliocytoma of the cerebellum (Lhermitte–Duclos disease): a case report
| Autor: | Yoshihiro Numagami, Mitsuomi Kaimori, Michiharu Nishijima, Shinjitsu Nishimura, Tomoo Inoue, Nakamasa Hayashi |
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| Rok vydání: | 2007 |
| Předmět: |
Cancer Research
Cerebellum Pathology medicine.medical_specialty Lhermitte–Duclos disease Lesion Cerebellar hemisphere medicine Humans Ataxic Gait Gangliocytoma Brain Diseases medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged medicine.disease Immunohistochemistry Magnetic Resonance Imaging medicine.anatomical_structure Oncology Female Neurology (clinical) Brainstem medicine.symptom Hamartoma Syndrome Multiple business |
| Zdroj: | Brain Tumor Pathology. 24:25-29 |
| ISSN: | 1861-387X 1433-7398 |
| Popis: | Lhermitte-Duclos disease is a rare clinical entity characterized by slow deformation of the cerebellar lesion. A 53-year-old woman presented with Lherimitte-Duclos disease manifesting as ataxic gait, occipital headache, and loss of consciousness. Magnetic resonance imaging demonstrated striated and laminar pattern lesions in the right cerebellar hemisphere and vermis. She underwent subtotal removal of the vermis compressing the brainstem, but the cerebellar hemisphere appeared normal and was preserved. Histological findings were consistent with Lherimitte-Duclos disease. Two years later, magnetic resonance imaging revealed enlargement of the right hemispheric lesion. Intraoperative appearance of the hemisphere demonstrated marked enlargement of the folia. Subtotal removal was performed. Histological examination showed no malignant findings. Lhermitte-Duclos disease may recur, and should be carefully followed up as a low-grade neoplasm, not as a hamartomatous disorder. |
| Databáze: | OpenAIRE |
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