Morphometry of Left Frontal and Temporal Poles Predicts Analogical Reasoning Abilities

Autor: Emmanuelle Volle, Frederic Humbert, Marika Urbanski, Michel Thiebaut de Schotten, Clarisse Aichelburg, Richard Levy
Přispěvatelé: Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Service de Médecine et de Réadaptation, Hôpitaux de Saint-Maurice, Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of psychiatry-King‘s College London, Center for NeuroImaging Research-Human MRI Neuroimaging core facility for clinical research [ICM Paris] (CENIR), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), HAL-UPMC, Gestionnaire, Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS), Centre de Neuro-Imagerie de Recherche (CENIR), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Adult
Male
Aging
Cognitive Neuroscience
Analogy
Neuropsychological Tests
050105 experimental psychology
Developmental psychology
Thinking
03 medical and health sciences
Cellular and Molecular Neuroscience
Young Adult
0302 clinical medicine
medicine
Connectome
Reaction Time
Arcuate fasciculus
Humans
0501 psychology and cognitive sciences
[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Set (psychology)
Prefrontal cortex
Aged
Temporal cortex
Sex Characteristics
05 social sciences
Novelty
Middle Aged
analogy
Temporal Lobe
Frontal Lobe
Functional imaging
medicine.anatomical_structure
Diffusion Magnetic Resonance Imaging
rostral prefrontal cortex
frontal pole
Educational Status
Regression Analysis
reasoning
Female
[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Psychology
030217 neurology & neurosurgery
morphometry
Cognitive psychology
Tractography
Zdroj: Cerebral Cortex
Cerebral Cortex, 2016, 26 (3), pp.915-932. ⟨10.1093/cercor/bhu254⟩
Cerebral Cortex, Oxford University Press (OUP), 2016, 26 (3), pp.915-932. ⟨10.1093/cercor/bhu254⟩
ISSN: 1047-3211
1460-2199
Popis: International audience; Analogical reasoning is critical for making inferences and adapting to novelty. It can be studied experimentally using tasks that require creating similarities between situations or concepts, i.e., when their constituent elements share a similar organization or structure. Brain correlates of analogical reasoning have mostly been explored using functional imaging that has highlighted the involvement of the left rostrolateral prefrontal cortex (rlPFC) in healthy subjects. However, whether inter-individual variability in analogical reasoning ability in a healthy adult population is related to differences in brain architecture is unknown. We investigated this question by employing linear regression models of performance in analogy tasks and voxel-based morphometry in 54 healthy subjects. Our results revealed that the ability to reason by analogy was associated with structural variability in the left rlPFC and the anterior part of the inferolateral temporal cortex. Tractography of diffusion-weighted images suggested that these 2 regions have a different set of connections but may exchange information via the arcuate fasciculus. These results suggest that enhanced integrative and semantic abilities supported by structural variation in these areas (or their connectivity) may lead to more efficient analogical reasoning.
Databáze: OpenAIRE
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