Antifungal lock therapy with combined 70% ethanol and micafungin in a critically ill infant

Autor:	Bianca Maria Goffredo, Imma Savarese, Cinzia Auriti, Fiammetta Piersigilli, Giuseppe Bianco, Andrea Dotta, Iliana Bersani
Rok vydání:	2014
Předmět:	Microbiology (medical) Male medicine.medical_specialty Parenteral Nutrition Record locking Antifungal Agents medicine.medical_treatment Critical Illness Lumen (anatomy) Micafungin Sodium Echinocandins Lipopeptides Candida albicans medicine Central Venous Catheters Humans Intensive care medicine Ethanol business.industry Micafungin Candidemia Infant bacterial infections and mycoses Antimicrobial Failure to Thrive Catheter Infectious Diseases Parenteral nutrition Anesthesia Catheter-Related Infections Pediatrics Perinatology and Child Health business Central venous catheter medicine.drug
Zdroj:	The Pediatric infectious disease journal. 33(4)
ISSN:	1532-0987
Popis:	So-called lock therapy, consisting of high concentrations of antimicrobials instilled into the lumen of the catheter, has been suggested avoid central venous catheter removal during fungal infection. We report a baby who developed catheter-related candidemia. Systemic antifungal treatment did not resolve the candidemia. Lock therapy with 0.3 mL of ethanol 70% and micafungin sodium 5 mg/L was added to the therapy, and blood cultures became sterile.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30c128eda4acfac4b6b8cacfeddb5b5 https://pubmed.ncbi.nlm.nih.gov/24637514 Zobrazit plný text záznamu