Mycobactericidal activity of glutaraldehyde solutions
| Autor: | V Montalbine, F M Collins |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Microbiology (medical)
Aldehydes Aqueous solution Chromatography biology Chemistry Kinetics Microbial Sensitivity Tests Mycobacterium tuberculosis Hydrogen-Ion Concentration biology.organism_classification Mycobacterium chemistry.chemical_compound Biochemistry Glutaral Sodium bisulfite Mycobacterium tuberculosis H37Rv Glutaraldehyde Disinfectants Research Article |
| Zdroj: | Journal of Clinical Microbiology. 4:408-412 |
| ISSN: | 1098-660X 0095-1137 |
| DOI: | 10.1128/jcm.4.5.408-412.1976 |
| Popis: | Aqueous solutions of alkaline glutaraldehyde (buffered at pH 8.5) inactivated a standard suspension of Mycobacterium tuberculosis H37Rv faster than the corresponding acid (pH 3.7 preparation. Quantitative differences in the rate of inactivation of eight other species of Mycobacterium were determined using a 1% solution of alkaline glutaraldehyde and inactivation of residual glutaraldehyde with 1% sodium bisulfite solution. Variations in the rate of kill were observed between the various mycobacterial species tested, but such differences were probably not sufficiently large to be of practical importance. A 2% alkaline glutaraldehyde solution inactivated 10(5) viable M. tuberculosis cells present on the surface of porcelain penicylinders within 5 min at 18 degrees C. This rate of inactivation was faster than in the acidic solution. |
| Databáze: | OpenAIRE |
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