Electrical impedance tomography monitoring in acute respiratory distress syndrome patients with mechanical ventilation during prolonged positive end-expiratory pressure adjustments

Autor: Sheng Hsiang Lin, Jen Suo Cheng, Wei Chi Lin, Yen Fen Ko, Chang Wen Chen, Chia Fu Hsu, Kuo-Sheng Cheng
Rok vydání: 2014
Předmět:
Adult
Male
ARDS
Respiratory rate
medicine.medical_treatment
Positive-Pressure Respiration
03 medical and health sciences
0302 clinical medicine
Fraction of inspired oxygen
Electric Impedance
Tidal Volume
Medicine
Humans
030212 general & internal medicine
Tomography
Tidal volume
Positive end-expiratory pressure
Aged
Medicine(all)
Mechanical ventilation
Aged
80 and over

lcsh:R5-920
Respiratory Distress Syndrome
business.industry
030208 emergency & critical care medicine
General Medicine
Oxygenation
acute respiratory distress syndrome
respiratory system
Middle Aged
medicine.disease
respiratory tract diseases
Anesthesia
Linear Models
Arterial blood
Female
lcsh:Medicine (General)
business
therapeutics
electrical impedance tomography
positive end-expiratory pressure
circulatory and respiratory physiology
Zdroj: Journal of the Formosan Medical Association, Vol 115, Iss 3, Pp 195-202 (2016)
ISSN: 0929-6646
Popis: Background/purposeThe time required to reach oxygenation equilibrium after positive end-expiratory pressure (PEEP) adjustments in mechanically ventilated patients with acute respiratory distress syndrome (ARDS) is unclear. We used electrical impedance tomography to elucidate gas distribution and factors related to oxygenation status following PEEP in patients with ARDS.MethodsNineteen mechanically ventilated ARDS patients were placed on baseline PEEP (PEEPB) for 1 hour, PEEPB − 4 cmH2O PEEP (PEEPL) for 30 minutes, and PEEPB + 4 cmH2O PEEP (PEEPH) for 1 hour. Tidal volume and respiratory rate were similar. Impedance changes, respiratory parameters, and arterial blood gases were measured at baseline, 5 minutes, and 30 minutes after PEEPL, and 5 minutes, 15 minutes, 30 minutes, and 1 hour after PEEPH.ResultsPaO2/fraction of inspired oxygen (P/F ratio) decreased quickly from PEEPB to PEEPL, and stabilized 5 minutes after PEEPL. However the P/F ratio progressively increased from PEEPL to PEEPH, and a significantly higher P/F ratio and end-expiratory lung impedance were found at 60 minutes compared to 5 minutes after PEEPH. The end-expiratory lung impedance level significantly correlated with P/F ratio (p
Databáze: OpenAIRE