Nitrogen-13 ammonia perfusion imaging: Relation to metabolic imaging
| Autor: | Ernst E. van der Wall, L.J. Gerhards, Eduard G. M. D’Haene, Menco G. Niemeyer, Aaf F. M. Kuijper |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Cardiomyopathy
Dilated Cardiomyopathy Hemodynamics Coronary Disease Perfusion scanning Coronary artery disease Coronary circulation Ammonia Coronary Circulation medicine Humans Nitrogen Radioisotopes medicine.diagnostic_test business.industry Myocardium Heart Blood flow Cardiomyopathy Hypertrophic medicine.disease medicine.anatomical_structure Positron emission tomography Imaging technology Cardiology and Cardiovascular Medicine Nuclear medicine business Tomography Emission-Computed |
| Zdroj: | American Heart Journal. 125:848-854 |
| ISSN: | 0002-8703 |
| Popis: | PET provides an advanced imaging technology that permits the accurate definition of regional tracer distribution. In combination with N-13 ammonia, PET allows for the sensitive and specific detection of coronary artery disease. Results of several studies indicate the superiority of this approach compared with standard thallium-201 tomographic imaging. In addition, regional blood flow can be accurately measured with N-13 ammonia PET, and this approach can be used in conjunction with pharmacologic stress imaging to quantify regional flow reserve. In combination with metabolic markers, N-13 ammonia is capable of assessing myocardial viability. Furthermore, the N-13 ammonia PET approach may differentiate among various forms of cardiomyopathy. More studies are needed to define the cost-benefit ratio of the N-13 ammonia PET technique for the management of patients with coronary artery disease or cardiomyopathy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|