Microbiota and their role in the pathogenesis of oral mucositis
| Autor: | Andrea M. Stringer, T. Van de Wiele, T De Ryck, Dorothy M. K. Keefe, Barbara Vanhoecke |
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| Přispěvatelé: | Vanhoecke, B, De Ryck, T, Stringer, A, Van de Wiele, T, Keefe, D |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Cancer therapy chemotherapy biofilm Pathogenesis oral Oral Microbiota Risk Factors Internal medicine microbiota medicine Mucositis Humans In patient General Dentistry radiotherapy Mouth Stomatitis Chemotherapy business.industry Microbiota Incidence (epidemiology) Mouth Mucosa medicine.disease Surgery Radiation therapy mucositis Otorhinolaryngology business |
| Zdroj: | Oral Diseases. 21:17-30 |
| ISSN: | 1601-0825 1354-523X |
| DOI: | 10.1111/odi.12224 |
| Popis: | Oral mucositis in patients undergoing cancer therapy is a significant problem. Its prevalence ranges between 20 and 100%, depending on treatment type and protocols and patient-based variables. Mucositis is self-limiting when uncomplicated by infection. Unfortunately, the incidence of developing a local or systemic infection during the course of the treatment is very high. At this stage, it is unclear which role oral microbiota play in the onset, duration, and severity of oral mucositis. Nevertheless, there is growing interest in this underexplored topic, and new studies are being undertaken to unravel their impact on the pathogenesis of mucositis. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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