Trend in antibiotic prescription to children aged 0–6 years old in the capital region of Denmark between 2009 and 2018: Differences between municipalities and association with socioeconomic composition

Autor: Volkert Siersma, Maria Louise Veimer Jensen, Sif Binder Larsen, Christine Winther Bang, Lars Bjerrum, Jette Nygaard Jensen
Rok vydání: 2021
Předmět:
Zdroj: The European Journal of General Practice
article-version (VoR) Version of Record
European Journal of General Practice, Vol 27, Iss 1, Pp 257-263 (2021)
Larsen, S B, Jensen, M L V, Bjerrum, L, Siersma, V, Bang, C W & Jensen, J N 2021, ' Trend in antibiotic prescription to children aged 0-6 years old in the capital region of Denmark between 2009 and 2018 : Differences between municipalities and association with socioeconomic composition ', The European Journal of General Practice, vol. 27, no. 1, pp. 257-263 . https://doi.org/10.1080/13814788.2021.1965121
ISSN: 1751-1402
1381-4788
DOI: 10.1080/13814788.2021.1965121
Popis: BACKGROUND: To curb future antibiotic resistance it is important to monitor and investigate current prescription patterns of antibiotics.OBJECTIVES: To examine trends in antibiotic prescription to children aged 0-6 years old and the association with socioeconomic status of municipalities in the Capital region of Denmark between 2009 and 2018.METHODS: This is a register-based study combining data on antibiotic treatments from 2009 to 2018, inhabitant-data and socioeconomic municipality scores. Subjects were children aged 0-6 years, residing in the Capital Region of Denmark. The study quantifies the use of antibiotics as number of antibiotic treatments/1000 inhabitants/year (TIY), inhabitants defined as children aged 0-6. Socioeconomic status of the municipalities is evaluated by a score from 3 to 12.RESULTS: The average TIY of the municipalities decreased from 741.2 [95%CI 689.3-793.2] in 2009 to 348.9 [329.4-368.4] in 2018. The difference between the highest and lowest prescribing municipalities was reduced from 648.3 TIY in 2009-212.5 TIY in 2018. The average increase in TIY per unit increase in socioeconomic municipality score changed from 20.05 [7.69-31.06] in 2009 to -4.58 [-16.02-5.60] in 2018, representing a decreasing association between socioeconomic municipality score and use of antibiotic in the respective municipalities.CONCLUSION: The trend in antibiotic prescription to children aged 0-6 years old decreased substantially in all the investigated municipalities in the 10-year study period. Local differences in prescription rates declined towards a more uniform prescription pattern across municipalities and association with socioeconomic status of the municipalities was reduced.
Databáze: OpenAIRE