Carbon-laden macrophages in pleural fluid of crack smokers
| Autor: | M.I.A.C. Ellen Greenebaum M.D., Baljit Singh, Randolph Cole |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Lung Neoplasms Histology Bronchopleural fistula Malignancy Pathology and Forensic Medicine HIV Seropositivity Parenchyma medicine Humans Tuberculosis Sarcoma Kaposi Acquired Immunodeficiency Syndrome Lung medicine.diagnostic_test business.industry Macrophages Pneumonia Pneumocystis Smoking General Medicine Hepatitis A Middle Aged respiratory system Hepatitis B medicine.disease Hepatitis C Carbon respiratory tract diseases Pulmonary embolism Pleural Effusion Pneumonia Bronchoalveolar lavage medicine.anatomical_structure Crack Cocaine Sarcoma Cardiomyopathies business |
| Zdroj: | Diagnostic Cytopathology. 13:316-319 |
| ISSN: | 1097-0339 8755-1039 |
| DOI: | 10.1002/dc.2840130408 |
| Popis: | Carbon-laden macrophages in bronchoalveolar lavage have been noted to be associated with a history of crack smoking. We report herein the finding of carbon-laden macrophages in four cytological preparations of pleural fluid from two crack smokers. The etiology of the two patients' pleural effusions differed; neither had a bronchopleural fistula. Patient 1 had AIDS, Pneumocystis carinii pneumonia, and Kaposi's sarcoma of the right lung with an associated bilateral pleural effusion. Patient 2 was HIV seropositive, had pulmonary tuberculosis, hepatitis A, B, and C, cardiomyopathy, pulmonary embolism, and bilateral pleural effusions, the latter of which were probably due to cardio-pulmonary dysfunction. An additional two crack smokers with pleural effusions due to malignancy, one primary pulmonary adenocarcinoma and the other metastatic melanoma, did not have carbon-like material in their pleural fluid cytology. We hypothesize that intracellular accumulation of carbonaceous material in the lung parenchyma and pleural space occurs when normal clearance mechanisms are overwhelmed. |
| Databáze: | OpenAIRE |
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