Impact of Knowledge-Based Iterative Model Reconstruction on Image Quality and Hemodynamic Parameters in Dynamic Myocardial Computed Tomography Perfusion Using Low-Tube-Voltage Scan: A Feasibility Study
Autor: | Takaaki Hosokawa, Teruyoshi Uetani, Teruhito Kido, Takanori Kouchi, Hikaru Nishiyama, Teruhito Mochizuki, Yuki Tanabe, Akira Kurata, Naoto Kawaguchi, Tomoyuki Kido |
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Rok vydání: | 2019 |
Předmět: |
Male
Computed tomography perfusion Image quality Computed Tomography Angiography Knowledge Bases Cardiac-Gated Imaging Techniques Hemodynamics Contrast Media Coronary Artery Disease Coronary Angiography 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Multidetector Computed Tomography Medicine Humans Radiology Nuclear Medicine and imaging Aged Retrospective Studies Iterative and incremental development Radon transform business.industry Low tube voltage Blood flow Middle Aged Iopamidol Exercise Test Feasibility Studies Radiographic Image Interpretation Computer-Assisted Female business 030217 neurology & neurosurgery Algorithms Biomedical engineering |
Zdroj: | Journal of computer assisted tomography. 43(5) |
ISSN: | 1532-3145 |
Popis: | OBJECTIVE Knowledge-based iterative model reconstruction (IMR) yields diagnostically acceptable image quality in low-dose static computed tomography (CT). We aimed to evaluate the feasibility of IMR in dynamic myocardial computed tomography perfusion (CTP). METHODS We enrolled 24 patients who underwent stress dynamic CTP using a 256-slice CT. Images were reconstructed using filtered back projection (FBP), hybrid IR, and IMR. Image quality and hemodynamic parameters were compared among three algorithms. RESULTS Qualitative image quality and contrast-to-noise ratio were significantly higher by IMR than by FBP or hybrid IR (visual score: 4.1 vs. 3.0 and 3.5; contrast-to-noise ratio: 12.4 vs. 6.6 and 8.4; P < 0.05). No significant difference was observed among algorithms in CTP-derived myocardial blood flow (1.68 vs. 1.73 and 1.70 mL/g/min). CONCLUSIONS The use of knowledge-based iterative model reconstruction improves image quality without altering hemodynamic parameters in low-dose dynamic CTP, compared with FBP or hybrid IR. |
Databáze: | OpenAIRE |
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