Accessories to Addiction
| Autor: | Ann E. Kelley, Craig A. Schiltz |
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| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Neuron. 42(2):181-183 |
| ISSN: | 0896-6273 |
| DOI: | 10.1016/s0896-6273(04)00223-5 |
| Popis: | The prefrontal cortex mediates many aspects of addiction. In this issue of Neuron, Bowers et al. demonstrate that an activator of G protein signaling (AGS3) is persistently upregulated in the prefrontal cortex after cessation of chronic cocaine treatment. Furthermore, they find that AGS3 is responsible for altered behavior, such as enhanced drug seeking, and altered neurotransmission in cocaine-treated rats, representing a novel therapeutic target. |
| Databáze: | OpenAIRE |
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