Papillary in situ and intramucosal adenocarcinoma of the lower third of common bile duct. A report and review of the literature

Autor: Germán E. Mendoza-Barrrera, Fredy Chablé-Montero, Liz Nicole Toapanta-Yanchapaxi, Mario L. Roca-Cabrera, Eduardo E. Montalvo-Javé, Carlos López-Caballero, Fernando Rojas-Mendoza
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Annals of Hepatology, Vol 14, Iss 3, Pp 425-429 (2015)
ISSN: 1665-2681
Popis: We report the case of a 37-year-old woman with no relevant medical history. She was admitted to the hospital for epigastric pain related with food intake for 4 days; the pain did not improve with symptomatic management. A laparoscopic cholecystectomy due to acute lithiasic cholecystitis was performed. However, after 4 days, postoperative painless jaundice was evident; thus, endoscopic retrograde cholangiopancreatography was performed, which revealed an amputation of intrapancreatic common bile duct, as well as secondary intra- and extrahepatic bile duct dilatation. Brushing of the distal portion of the common bile duct revealed a well-differentiated adenocarcinoma. Therefore, a Whipple procedure with pylorus preservation was performed. Pathologic diagnosis of a papillary in situ adenocarcinoma with two microscopic foci of microinvasion was established. The pathologic Tumor-Node-Metastasis (TNM) stage was pT1, pN0, pM0, R0. The patient is asymptomatic and disease-free 24 months after surgery. In general, adenocarcinomas of the extrahepatic bile ducts are uncommon and have a poor prognosis. However, symptomatic patients with early disease stages are even rarer and can be cured surgically.
Databáze: OpenAIRE