High prevalence of exercise-induced ischemia in the asymptomatic limb of patients with apparently strictly unilateral symptoms and unilateral peripheral artery disease
| Autor: | Myriam Ammi, Pierre Abraham, Jean-Marie Chretien, Pascal Bauer, Samir Henni, Xavier Papon, Jeanne Hersant, Jean Picquet, Mickael Daligault, Tanguy Le Meliner |
|---|---|
| Přispěvatelé: | Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Physiopathologie Cardiovasculaire et Mitochondriale (MITOVASC), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
lcsh:Diseases of the circulatory (Cardiovascular) system Time Factors Arterial disease [SDV]Life Sciences [q-bio] Disease 030204 cardiovascular system & hematology 0302 clinical medicine Prevalence Medicine Pharmacology (medical) Treadmill Original Research treadmill testing High prevalence Exercise Tolerance exercise Middle Aged 3. Good health diabetes mellitus Cardiology Female France medicine.symptom Cardiology and Cardiovascular Medicine medicine.medical_specialty Ischemia walking impairment Asymptomatic 03 medical and health sciences peripheral arterial disease Internal medicine Diabetes mellitus Humans Retrospective Studies claudication business.industry transcutaneous oxygen pressure Intermittent Claudication medicine.disease ankle brachial index body regions Regional Blood Flow lcsh:RC666-701 Exercise Test lower limb business Claudication 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Therapeutic Advances in Cardiovascular Disease Therapeutic Advances in Cardiovascular Disease, Vol 13 (2019) Therapeutic Advances in Cardiovascular Disease, 2019, 13, pp.1-12. ⟨10.1177/1753944718819063⟩ |
| ISSN: | 1753-9455 1753-9447 |
| DOI: | 10.1177/1753944718819063⟩ |
| Popis: | Background: The prevalence of exercise-induced ischemia in the asymptomatic limb of patients with unilateral claudication based on history and treadmill evaluation, and with unilateral ipsilateral peripheral artery disease (i.e ankle-to-brachial systolic pressure index Methods: We detected exercise-induced ischemia in the asymptomatic limb of patients with apparently unilateral claudication. Among 6059 exercise-oximetry tests performed in 3407 nondiabetic and 961 diabetic patients. We estimated the intensity of ischemia in the both limb (buttocks and calves) using the lowest minimum value of the decrease from rest of oxygen pressure (DROP; limb changes minus chest changes from rest), with significant ischemia defined as DROP lower than −15 mmHg. Results: We found 152 tests performed in 142 nondiabetic patients and 40 tests performed in 38 diabetic patients. The asymptomatic limb showed significant ischemia in 46.7% and 37.5% of the tests. Strictly unilateral exercise-induced claudication with apparently unilateral peripheral artery disease was rare (Conclusion: The asymptomatic limb of patients with peripheral artery disease should not be considered a normal limb. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|