Atypical presentation of multicentric Castleman disease in a pediatric patient: pleural and pericardial effusion
| Autor: | Derya Ozyoruk, Tulin Sayli, Alkım Öden Akman, Nilgün Çakar, Unsal Han, Özge Başaran |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Adolescent Pleural effusion Pericardial effusion Pericardial Effusion Diagnosis Differential 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Humans Hyaline business.industry Castleman Disease Castleman disease nutritional and metabolic diseases medicine.disease eye diseases Pleural Effusion Radiography Pediatric patient Echocardiography 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Lymph Differential diagnosis Presentation (obstetrics) business |
| Zdroj: | European Journal of Pediatrics. 175:873-876 |
| ISSN: | 1432-1076 0340-6199 |
| Popis: | Castleman disease (CD) is a rare poorly understood lymphoproliferative disorder. Pediatric onset CD has been reported before. However, most of them have benign unicentric pattern. Multicentric CD (MCD) is quite rare in children. Herein, we report a 13-year-old adolescent boy with MCD of the hyaline vascular variant presenting with pleural and pericardial effusion, which is an uncommon presentation.MCD should be considered in the differential diagnosis of pleural and/or pericardial effusion with unexplained lymph nodes in children. What is Known •Pediatric Castleman disease (CD) most commonly occurs in the unicentric form, which typically is asymptomatic and cured by lymph node excision. •The diagnosis of MCD can be difficult owing to the heterogeneity of presentation and potential for nonspecific multisystem involvement. What is New •A 13-year-old adolescent boy was diagnosed with MCD of the hyaline vascular variant presenting with pleural and pericardial effusion, which is an uncommon presentation. •In a pediatric patient with fever, pleural-pericardial effusion and multiple lymph nodes, MCD should be considered in differantial diagnosis. |
| Databáze: | OpenAIRE |
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