Subjective audiological tests and transient evoked otoacoustic emissions in patients with rheumatoid arthritis: analysis of the factors affecting hearing levels
Autor: | Ihsan Ünlüsoy, Oğuzhan Dikici, Nuray Bayar Muluk, Aliye Tosun |
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Přispěvatelé: | Kırıkkale Üniversitesi |
Rok vydání: | 2008 |
Předmět: |
Hearing levels
Adult Male medicine.medical_specialty Transient evoked otoacoustic emissions (TEOAEs) Otoacoustic Emissions Spontaneous Audiology Pure tone audiometry Arthritis Rheumatoid Risk Factors medicine Humans High frequency audiometry Prospective Studies Hearing Loss Aged medicine.diagnostic_test business.industry Auditory Threshold General Medicine Tympanometry Middle Aged medicine.disease Conductive hearing loss Audiometry Evoked Response Otorhinolaryngology Acoustic Impedance Tests Erythrocyte sedimentation rate Rheumatoid arthritis Rheumatoid arthritis (RA) Case-Control Studies Audiometry Pure-Tone Sensorineural hearing loss Female Audiometry business Hearing functions |
Zdroj: | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 266(11) |
ISSN: | 1434-4726 |
Popis: | WOS: 000270437200007 PubMed: 19360433 We investigated hearing functions in patients with rheumatoid arthritis (RA) using audiological tests and transient evoked otoacoustic emissions (TEOAEs). The study group consisted of 20 adult patients with RA (7 males, 13 females); 20 adult healthy subjects without RA (7 males, 13 females) were recruited as controls. All patients were evaluated by pure tone audiometry, high frequency audiometry, tympanometry and TEOAEs. There were no statistical differences between the study and control groups with respect to the pure tone and high frequency audiometries. TEOAE results of 1.0-2.0 kHz % and of 1.5 and 3.0 kHz amplitude values were significantly lower, and ipsilateral stapes reflex threshold value at 1.0 kHz was significantly higher in the study group when compared to respective values in the control group. In elderly patients and those with longer disease duration, RA nodules and higher methotrexate cumulative doses, hearing thresholds increased and TEOAE values decreased. In active stage of the disease, hearing thresholds diminished and in higher Brinkman Index values, TEOAE values decreased. Compliance values decreased in patients with higher Ritchie Articular Index, C-reactive protein, erythrocyte sedimentation rate and platelet counts, and longer disease duration. Sensorineural hearing loss is generally observed in patients with RA, and this condition may be detected by TEOAEs in an early period of the disease. Inflammation during the active stage of the disease and the subsequent fibrosis may cause conductive hearing loss of varying degrees. In those patients detected as having initiation of TEOAE decrease, vasodilator treatment and antioxidant drugs may be useful in protecting the inner ear. |
Databáze: | OpenAIRE |
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