Nutrition and the ageing brain: Moving towards clinical applications

Autor: Philip W.J. Burnet, Sandrine Thuret, Emma Flanagan, Martijn C. de Wilde, Mary Yannakoulia, Vittorio Calabrese, Cécilia Samieri, David Vauzour, Thomas Hartung, Nancy B. Emerson Lombardo, Tobias Hartmann, Lucie Geurts, Stephen C. Cunnane, Kieran Tuohy, Daniel J. Lamport, Silvia Turroni, Louise Dye, Lorraine Brennan, Jonathan A. Farrimond, A. David Smith, Jeremy P. E. Spencer, Marko Kalliomäki, Martin Verkuijl, Wim Vanden Berghe, Giorgio La Fata, Karin Verzijden, Gunther G. Kuhnle, Aleix Sala-Vila
Přispěvatelé: Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Flanagan E., Lamport D., Brennan L., Burnet P., Calabrese V., Cunnane S.C., de Wilde M.C., Dye L., Farrimond J.A., Emerson Lombardo N., Hartmann T., Hartung T., Kalliomaki M., Kuhnle G.G., La Fata G., Sala-Vila A., Samieri C., Smith A.D., Spencer J.P.E., Thuret S., Tuohy K., Turroni S., Vanden Berghe W., Verkuijl M., Verzijden K., Yannakoulia M., Geurts L., Vauzour D.
Rok vydání: 2020
Předmět:
0301 basic medicine
Gerontology
Aging
Population ageing
medicine.medical_specialty
Population
Nutritional Status
Biochemistry
LEHA
Healthy Aging
03 medical and health sciences
0302 clinical medicine
ddc:570
Healthy ageing
medicine
Humans
Dementia
Cognitive decline
education
Biology
Molecular Biology
2. Zero hunger
education.field_of_study
Brain
Healthy ageing
Preventative diet
Microbiota
Neuroprotection
Cognitive ageing
Cognitive ageing
Microbiota
Public health
[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences
Brain
medicine.disease
Neuroprotection
Diet
3. Good health
Settore AGR/15 - SCIENZE E TECNOLOGIE ALIMENTARI
030104 developmental biology
Neurology
Ageing
Preventative diet
Life expectancy
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Human medicine
Psychology
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
030217 neurology & neurosurgery
Biotechnology
Zdroj: Ageing research reviews
Ageing Research Reviews-ARR
Ageing Research Reviews-ARR, Elsevier Masson, 2020, 62, pp.101079. ⟨10.1016/j.arr.2020.101079⟩
ISSN: 1568-1637
1872-9649
DOI: 10.1016/j.arr.2020.101079
Popis: International audience; The global increases in life expectancy and population have resulted in a growing ageing population and with it a growing number of people living with age-related neurodegenerative conditions and dementia, shifting focus towards methods of prevention, with lifestyle approaches such as nutrition representing a promising avenue for further development.This overview summarises the main themes discussed during the 3rd Symposium on “Nutrition for the Ageing Brain: Moving Towards Clinical Applications” held in Madrid in August 2018, enlarged with the current state of knowledge on how nutrition influences healthy ageing and gives recommendations regarding how the critical field of nutrition and neurodegeneration research should move forward into the future.Specific nutrients are discussed as well as the impact of multi-nutrient and whole diet approaches, showing particular promise to combatting the growing burden of age-related cognitive decline. The emergence of new avenues for exploring the role of diet in healthy ageing, such as the impact of the gut microbiome and development of new techniques (imaging measures of brain metabolism, metabolomics, biomarkers) are enabling researchers to approach finding answers to these questions. But the translation of these findings into clinical and public health contexts remains an obstacle due to significant shortcomings in nutrition research or pressure on the scientific community to communicate recommendations to the general public in a convincing and accessible way. Some promising programs exist but further investigation to improve our understanding of the mechanisms by which nutrition can improve brain health across the human lifespan is still required.
Databáze: OpenAIRE
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