Comparison of agglutination, complement fixation and immunofluorescence tests in Campylobacter jejuni infections
| Autor: | K. C. Watson, E. J. C. Kerr |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Diarrhea
Serotype Immunology Fluorescent Antibody Technique Immunofluorescence Campylobacter jejuni Microbiology Serology Campylobacter fetus Antibody Specificity Agglutination Tests Campylobacter Infections medicine Humans biology medicine.diagnostic_test Complement Fixation Tests Public Health Environmental and Occupational Health biology.organism_classification Complement fixation test Virology Agglutination (biology) Evaluation Studies as Topic biology.protein Antibody Research Article |
| Zdroj: | Journal of Hygiene. 88:165-171 |
| ISSN: | 0022-1724 |
| DOI: | 10.1017/s0022172400070042 |
| Popis: | SummaryGood antibody responses usually follow infection with Campylobacter jejuni. A comparison of agglutination, complement fixation and immunofluorescence tests was done on 55 sera from 40 sporadic patients with diarrhoeal disease and positive cultures for C. jejuni. Results showed 82 % positive with immunofluorescence, 62 % by complement fixation but only 38 % by agglutination, using two reference strains COP and MEL as antigens. Overall 90 % of the 40 patients were positive by one or more serological tests. Paired sera from 15 patients showed a fourfold or greater rise in only five, confirming previous observations that antibody formation occurs early in the course of infection. Results also suggest that different test systems may be detecting antibodies of different specificities. Results confirm the value of serological tests, but further information on serotypes is required for selection of suitable reference strains. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|