Equivalent dose in 2 Gy (EQD2) to pelvic lymph nodes using volume based prescription for three brachytherapy applicators — a dosimetric retrospective analysis
| Autor: | Janaki Manur Gururajachar, Revathy T, Ram Charith Alva, Kirthi Koushik As, Mohan Kumar S, Nishant Vidyasagar, Arul Ponni Thiruraj |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cervical cancer
Co-60 Equivalent dose business.industry medicine.medical_treatment Brachytherapy brachytherapy HDR medicine.disease Pelvic lymph nodes Metastasis EQD2 medicine.anatomical_structure Oncology applicators medicine Radiology Nuclear Medicine and imaging Lymph External beam radiotherapy Nuclear medicine business Lymph node Research Paper pelvic lymph nodes |
| Zdroj: | Reports of Practical Oncology and Radiotherapy |
| ISSN: | 2083-4640 1507-1367 |
| Popis: | BACKGROUND: Pelvic lymph node (PLN) metastasis has been included in the FIGO staging, so there is a need to determine the dose contribution from brachytherapy to ascertain the total delivered dose to the pelvic lymph nodes in cervical cancer. The aim of the study was to calculate the equivalent dose in 2 Gy (EQD2) of the pelvic lymph nodes (PLNs) based on volume prescription using three applicators. Materials and methods: Forty-one patients who had undergone external beam radiotherapy followed by brachytherapy using tandem ovoids (TO), tandem ring (TR) and TO + free hand interstitial needles (TO + FH) applicators were taken for this study. 26 Gy in 4 fractions was prescribed to HRCTV. The external iliac node (ELN), internal iliac node (ILN) and obturator (OBT) were contoured and the median EQD2 of the lymph nodes was calculated. RESULTS: The median bilateral EQD2 values of ELN were 1.55 Gy (TR), 1.75 Gy (TO), 1.9 Gy (TO + FH), of ILN these were 2.57 Gy (TR), 3.27 Gy (TO), 3.04 Gy (TO + FH), and of OBT these were 3.69 Gy (TR), 4.46 Gy (TO), 4.69 Gy (TO + FH), respectively. The total median EQD2 values of TR, TO and TO + FH were 52.71 Gy, 53.03 Gy, and 53.88–62.73 Gy, respectively. CONCLUSION: Our study calculated the median EQD2 to the pelvic lymph nodes using three types of applicators in brachytherapy. This could serve as reference to decide on the EBRT boost dose while treating patients with enlarged pelvic lymph nodes. |
| Databáze: | OpenAIRE |
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