The existence of hypoglossal root ganglion cells in adult humans: potential clinical implications
Autor: | Mark E. Rogers, Robert Lott, Gina D. Chua, Aaron A. Cohen-Gadol, Diala El-Zammar, W. Jerry Oakes, David R. Kelly, Marios Loukas, R. Shane Tubbs, Mohammadali Mohajel Shoja |
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Rok vydání: | 2008 |
Předmět: |
Male
Nervous system Hypoglossal Nerve Cell Sympathetic nerve Pathology and Forensic Medicine Cadaver Humans Medicine Radiology Nuclear Medicine and imaging Ganglia Autonomic Aged Aged 80 and over Neurons Ganglia Sympathetic business.industry Anatomy Middle Aged Immunohistochemistry Ganglion Autonomic nervous system medicine.anatomical_structure Sympathetic Fibers Female Surgery business Neuroscience Hypoglossal nerve |
Zdroj: | Surgical and Radiologic Anatomy. 31:173-176 |
ISSN: | 1279-8517 0930-1038 |
DOI: | 10.1007/s00276-008-0422-6 |
Popis: | Ganglion cells of the hypoglossal nerve (HN) have been confirmed in certain animals but have been thought not to be present in man. To investigate for the presence of these structures in adult humans and if present, to verify their functionality, the present study was performed.We harvested adult cadaveric HN and observed for ganglion cells. Histological and immunohistochemical analyses were performed on all specimens.Ganglion cells were found in 33% of specimens. Using immunohistochemistry, we found that these ganglia were sympathetic in nature. Based on our findings, ganglion cells do exist in the human HN although they are located sporadically and are found inconstantly.Such information may be valuable in elucidating other functions of the HN and may aid in the histological diagnosis of this nerve. Additionally, pathology involving HN such as paragangliomas, are supported by our findings of the presence of autonomic ganglion cells in some HN specimens. |
Databáze: | OpenAIRE |
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