The prevalence of anti-rubella antibodies in women of childbearing age in Poland
| Autor: | M. Rawicz, Janusz Slusarczyk, Paulina Górska, Grzegorz Gniadek, Bozena Bucholc, T. Wysokiñska, W. Janaszek |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Enzyme-Linked Immunosorbent Assay Abortion medicine.disease_cause Antibodies Viral Rubella Congenital Rubella Prevalence Medicine Humans Pregnancy Congenital rubella syndrome General Veterinary General Immunology and Microbiology business.industry Obstetrics Public Health Environmental and Occupational Health Antibody titer Age Factors virus diseases Rubella virus medicine.disease Vaccination Infectious Diseases Immunoglobulin G Immunology Molecular Medicine Female Poland business |
| Zdroj: | Vaccine. 22(15-16) |
| ISSN: | 0264-410X |
| Popis: | Congenital rubella is a clinically serious problem, which is due to maternal infection with rubella virus during the first trimester of pregnancy. It may result in spontaneous abortion or in fetal infection leading to fetal birth defect. Maternal anti-rubella antibodies have a protective effect and they may prevent congenital rubella. Vaccination of 13-year-old girls in Poland was introduced in 1989. Vaccination coverage is above 95%. The presence of anti-rubella antibodies in maternal blood >15 IU/ml is indicative for immunity to rubella. Thus, the aim of the study was the evaluation of anti-rubella antibody levels in women 15-30 years old. Samples of that sera were collected from six provinces in Poland. We have observed the decrease of anti-rubella antibody titer together with increasing age of tested women. Among 1289 investigated women 135 [10.5%] did not have protective levels of anti-rubella antibodies. We have noticed large decline in protective anti-rubella antibodies in young women (19-22 years of age), who are just entering their prime childbearing years. |
| Databáze: | OpenAIRE |
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