Extensive cardiopulmonary resuscitation of preterm neonates at birth and mortality and developmental outcomes
| Autor: | Nicole Fischer, Amuchou Soraisham, Prakesh S. Shah, Anne Synnes, Yacov Rabi, Nalini Singhal, Joseph Y. Ting, Dianne Creighton, Deborah Dewey, Marilyn Ballantyne, Abhay Lodha, Prakesh S Shah, Jaideep Kanungo, Joseph Ting, Wendy Yee, Jennifer Toye, Carlos Fajardo, Zarin Kalapesi, Koravangattu Sankaran, Sibasis Daspal, Mary Seshia, Ruben Alvaro, Amit Mukerji, Orlando Da Silva, Chuks Nwaesei, Kyong-Soon Lee, Michael Dunn, Brigitte Lemyre, Kimberly Dow, Ermelinda Pelausa, Anie Lapoint, Christine Drolet, Bruno Piedboeuf, Martine Claveau, Marc Beltempo, Valerie Bertelle, Edith Masse, Roderick Canning, Hala Makary, Cecil Ojah, Luis Monterrosa, Julie Emberley, Jehier Afifi, Andrzej Kajetanowicz, Shoo K Lee, null Canadian Neonatal Follow-Up Network (CNFUN) Investigators, Thevanisha Pillay, Reg Sauvé, Leonora Hendson, Amber Reichert, Jaya Bodani, Diane Moddemann, Thierry Daboval, David Lee, Kevin Coughlin, Linh Ly, Edmond Kelly, Saroj Saigal, Paige Church, Patricia Riley, Thuy Mai Luu, Francine Lefebvre, Charlotte Demers, Sylvie Bélanger, Michael Vincer, Phil Murphy |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Canada medicine.medical_treatment education Motor Disorders Gestational Age 030204 cardiovascular system & hematology Emergency Nursing Odds 03 medical and health sciences 0302 clinical medicine Corrected Age Infant Mortality medicine Humans Cardiopulmonary resuscitation Retrospective Studies business.industry Delivery room Infant Newborn Gestational age Infant 030208 emergency & critical care medicine Odds ratio Cardiopulmonary Resuscitation 3. Good health Neurodevelopmental Disorders Infant Extremely Premature Emergency Medicine Premature Birth Female Outcome data Cardiology and Cardiovascular Medicine business Neonatal resuscitation Infant Premature Follow-Up Studies |
| Zdroj: | Resuscitation. 135 |
| ISSN: | 1873-1570 |
| Popis: | To compare mortality and neurodevelopmental outcomes of extremely low gestational age neonates who received delivery room extensive cardiopulmonary resuscitation (DR-CPR) to those who did not require DR-CPR.Preterm neonates born at29 weeks' gestational age between January 2010 and September 2011 and assessed at Canadian Neonatal Follow-Up Network centers were studied. Neonates who received DR-CPR were compared to those who did not require DR-CPR using univariate and multivariable analyses. The primary outcome was a composite of mortality or any neurodevelopmental impairment at 18 to 24 months corrected age defined as the presence of any one or more of the following: cerebral palsy; Bayley-III cognitive, language, or motor composite scores85 on any one of the components; sensorineural/mixed hearing loss or unilateral or bilateral visual impairment. Secondary outcomes were the individual components of the composite outcomes.Of the 2760 neonates born, 173 were excluded and remaining 2587 eligible neonates were included in our study. Of these 2068 had outcome data (80%) of whom 190 (9.2%) received DR-CPR. DR-CPR was independently associated with mortality or neurodevelopmental impairment (adjusted odds ratio [aOR] 1.76; 95% CI 1.21-2.55) and mortality alone (aOR1.94; 95% CI 1.33-2.83). DR-CPR was also associated with increased odds of motor impairment (aOR 2.03; 95% CI 1.28-3.23).In extremely low gestational age neonates, DR-CPR was associated with higher odds of the composite outcome of mortality or neurodevelopmental impairment, mortality alone, and lower motor scores at 18 to 24 months' corrected age. |
| Databáze: | OpenAIRE |
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