A multicenter survey of enteroscopy for the diagnosis of intestinal follicular lymphoma

Autor: Junji Shiode, Motowo Mizuno, Haruka Fukatsu, Haruhiko Kobashi, Atsushi Imagawa, Mamoru Nishimura, Toru Ueki, Katsuyoshi Takata, Seiji Kawano, Seiyu Suzuki, Hiroyuki Okada, Yoshinari Kawai, Shouichi Tanaka, Takashi Kitagawa, Masashi Araki, Tatsuya Toyokawa, Kazuhide Yamamoto, Masaya Iwamuro, Tadashi Yoshino, Tomohiko Mannami, Tomoki Inaba, Ryuta Takenaka, Akinobu Takaki, Akiyoshi Omoto
Rok vydání: 2015
Předmět:
Zdroj: Oncology Letters. 10:131-136
ISSN: 1792-1082
1792-1074
Popis: The importance of enteroscopy examinations to investigate the entire length of the small intestines has been emphasized in follicular lymphoma patients with intestinal involvement. The aim of the present study was to determine the current state of enteroscopy examinations, including the performance rate, and the prevalence of small intestinal lesions in a patient population in Japan. A retrospective multicenter survey of 17 institutions collected the case information of 110 follicular lymphoma patients with gastrointestinal involvement. The results of the enteroscopy examinations were reviewed, and in order to identify potential factors affecting the performance rate of enteroscopy, patient gender, age at lymphoma diagnosis, histopathological grade, clinical stage, the date of the initial diagnosis and the annual volume of enteroscopy at the institution were compared between the patients who underwent one or more enteroscopy procedures and the patients who did not undergo enteroscopy. A total of 34 patients (30.9%) underwent enteroscopy, and 24 of these (70.6%) presented with involvement in the jejunum and/or ileum. It was found that more patients diagnosed in recent years and more patients treated at an ultra-high volume institution (≥101 enteroscopy examinations/year) underwent an enteroscopy. In conclusion, although the prevalence of small intestinal lesions was high (70.6%) in the follicular lymphoma patients presenting with intestinal involvement, the performance rate of enteroscopy was only 30.9%, and thus the majority of the patients have not undergone enteroscopy examinations. Further investigation is required to define the clinical significance of enteroscopy at the initial diagnostic work-up and during the follow-up period of these patients.
Databáze: OpenAIRE