TRANSIENT HYPOXÆMIA DURING SLEEP IN CHRONIC BRONCHITIS AND EMPHYSEMA
| Autor: | H.M. Brash, Neil J. Douglas, V. Brezinova, D. C. Flenley, Peter M. A. Calverley, R. J. E. Leggett |
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| Rok vydání: | 1979 |
| Předmět: |
Adult
Male Chronic bronchitis Time Factors Hypertension Pulmonary Sleep REM Blood Pressure Polycythemia Pulmonary Artery Humans Medicine Bronchitis Hypoxia Aged Oxygen saturation (medicine) business.industry Respiration Hypoventilation General Medicine Oxygenation Middle Aged medicine.disease Pulmonary hypertension Oxygen Blood pressure Pulmonary Emphysema Anesthesia Chronic Disease Breathing Female medicine.symptom Sleep business Perfusion |
| Zdroj: | The Lancet. 313:1-4 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(79)90451-3 |
| Popis: | Arterial oxygenation, breathing pattern, and electroencephalogram were studied during sleep in patients with chronic bronchitis and emphysema and in healthy subjects. All of the 10 "blue and bloated" patients had episodes of transient hypoxaemia lasting 1--100 min, when their oxygen saturation fell by more than 10%, whereas such desaturation did not occur in 2 "pink and puffing" patients or in 4 healthy subjects. Hypoxaemic episodes usually occurred during the rapid-eye-movement stage of sleep. It is suggested that these hypoxaemic episodes result from a combination of hypoventilation and impaired ventilation/perfusion relationships and that these episodes may contribute to the development of the pulmonary hypertension and secondary polycythaemia which characterises "blue and bloated" patients. |
| Databáze: | OpenAIRE |
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