Structure, Content, and Bioactivity of Food-Derived Peptides in the Body
Autor: | Kenji Sato |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Peptide 01 natural sciences 03 medical and health sciences Functional food Functional Food In vivo Endopeptidases Animals Humans chemistry.chemical_classification 030109 nutrition & dietetics biology Food protein digestive oral and skin physiology 010401 analytical chemistry General Chemistry Exopeptidase In vitro 0104 chemical sciences Amino acid Bioavailability chemistry Biochemistry biology.protein Peptides General Agricultural and Biological Sciences |
Zdroj: | Journal of Agricultural and Food Chemistry. 66:3082-3085 |
ISSN: | 1520-5118 0021-8561 |
Popis: | Orally administered peptides are assumed to be degraded into amino acids in the body. However, our recent studies revealed some food-derived prolyl and pyroglutamyl peptides with 2-3 amino acid residues in the blood of humans and animals, while most of the peptides in the endoproteinase digest of food protein are degraded by exopeptidase. Some food-derived dipeptides in the body display in vitro and in vivo biological activities. These facts indicate that the biological activities of food-derived peptides in the body rather than those in food are crucial to understanding the mechanism of the beneficial effects of orally administered peptides. |
Databáze: | OpenAIRE |
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