New Recoverable Poly(ethylene glycol)-Supported C1-Diamino-oligothiophene Ligands for Palladium-Promoted Asymmetric Allylic Alkylation (AAA) Reactions
| Autor: | Achille Umani‐Ronchi, Maurizio Benaglia, Tommaso Quinto, Simona Tommasi, Marco Bandini |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Poly ethylene glycol
Chemistry Precipitation (chemistry) Chiral ligand Enantioselective synthesis chemistry.chemical_element General Chemistry General Medicine Dimethyl malonate Catalysis law.invention Tsuji–Trost reaction chemistry.chemical_compound law Polymer chemistry Thiophene Organic chemistry Filtration Palladium |
| Zdroj: | ChemInform. 37 |
| ISSN: | 1522-2667 0931-7597 |
| Popis: | A new class of chiral C 1 -symmetrical di-amino-oligothiophene ligands easy-grafted on a soluble polymeric support (MeOPEG 5000 ) is described. The diamines were found to be effective promoting agents for the [Pd(0)]-catalysed asymmetric allylic alkylation (AAA) of dimethyl malonate in high yields and excellent enantioselectivity (ee up to 99%). The supported chiral ligand was readily recovered by precipitation and filtration was recycled up to three times without an appreciable loss in activity. The recycle of the organometallic catalytic system was also investigated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text